Odontophrynus salvatori is a species of frog in the family Odontophrynidae. It is endemic to Brazil and known from its type locality in the Chapada dos Veadeiros National Park, from the Serra dos Pirineus State Park (both in the state of Goiás), and from the Federal District. Its natural habitat is Cerrado savanna, where it occurs on the ground near waterbodies. The tadpoles develop in small temporary streams. It is threatened by habitat loss caused by agricultural development and fires.