Hedwigidium integrifolium

<p>Scientists at the <a href="https://www.bath.ac.uk/" target="_blank" rel="noreferrer noopener">University of Bath</a> have achieved a breakthrough by harnessing the "super power" of a tropical <a href="https://www.earth.com/news/honey-bees-are-very-loyal-to-their-flower-patches/">flower</a>, potentially revolutionizing the pharmaceutical industry's approach to drug development. </p>



<p>The research, inspired by nature, focuses on creating more stable and effective drugs using a technique derived from Oldenlandia affinis, a small purple flower.</p>



<h2 class="wp-block-heading" id="h-seeking-more-effective-drugs">Seeking more effective drugs</h2>



<p>Traditionally, drug treatments target disease-related proteins to block their activity, either alleviating symptoms or curing the disease. However, the conventional method using small molecules has limitations, especially in blocking protein interactions.&nbsp;</p>



<p>The pharmaceutical industry is now exploring the use of small proteins called peptides, which could lead to improved drug discovery.</p>



<h2 class="wp-block-heading" id="h-new-drug-candidates-nbsp">New drug candidates&nbsp;</h2>



<p>The challenge with peptides and proteins as drug candidates is their structural vulnerability. They tend to unravel, are sensitive to high temperatures, and have difficulty penetrating cells, where many significant drug targets reside.&nbsp;</p>



<p>The University of Bath team has developed a novel solution to these issues. The technique involves creating "cyclic" proteins and peptides by joining their start and end points. This process enhances their stability against heat and chemicals and facilitates easier cell penetration.&nbsp;</p>



<h2 class="wp-block-heading" id="h-focus-of-the-study-nbsp">Focus of the study&nbsp;</h2>



<p>The experts utilized the enzyme OaAEP1 from Oldenlandia affinis, modifying it and integrating it into bacterial cells for mass production. This process simultaneously joins the proteins' ends in a single step.</p>



<p>While plants can naturally cyclicize proteins, it's a slow and low-yielding process. Chemical cyclization is an alternative but involves multiple steps and toxic solvents.&nbsp;</p>



<h2 class="wp-block-heading" id="h-key-insights">Key insights</h2>



<p>The bacterial system introduced by the Bath team is a significant improvement. This approach offers higher yields, uses sustainable biologically-friendly reagents, and simplifies the process, making it cheaper and greener.</p>



<p>To demonstrate their method's efficacy, the researchers applied their bacterial OaAEP1 technology to a protein called DHFR. They found that linking its head and tail ends increased its temperature resistance while maintaining its normal function.</p>



<h2 class="wp-block-heading" id="h-study-significance">Study significance</h2>



<p>Professor Jody Mason from the University of Bath’s Department of Life Sciences highlighted the significance of this discovery.&nbsp;</p>



<p>"Proteins and peptides are generally quite sensitive to heat, but cyclisation makes them much more robust," said Professor Mason. “The Oldenlandia plant naturally makes cyclic proteins as part of a defence mechanism to deter predators."</p>



<p>“So we’ve harnessed this flower super power by modifying OaAEP1 and combining it with existing bacterial protein-producing technology to create a really powerful tool that will help the drug discovery industry.”</p>



<h2 class="wp-block-heading" id="h-exciting-potential-applications-nbsp">Exciting potential applications&nbsp;</h2>



<p>Dr. Simon Tang, a research associate in the University of Bath Department of Life Sciences, explained that proteins and peptides are very promising as drug candidates, but a significant bottleneck for the development of new therapeutic treatments is producing enough of the stuff to reach patients without incurring an astronomical cost.</p>



<p>“Our new process lets the bacteria do all the work – the result is it’s also cleaner and greener, and because it has fewer steps, it is a lot simpler to do," said Dr. Tang.</p>



<p>“We’re really excited about the potential applications of this, not only for the pharmaceutical industry but other industries such as the food industry, detergent industry, in biotechnology, and in bioenergy production.”</p>



<p>The researchers have filed a patent for the technique. The study is published in the <a href="http://dx.doi.org/10.1021/jacsau.3c00591" target="_blank" rel="noreferrer noopener"><em>Journal of the American Chemical Society Gold</em></a>.</p>



<p>Image Credit: Peter Warren</p>



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'Super power' of a tropical flower will improve drug discovery

Scientists at the University of Bath have achieved a breakthrough...

<p>Scientists have uncovered a crucial connection between ocean oxygen levels and one of the most catastrophic marine <a href="https://www.earth.com/news/scientists-predict-a-new-mass-extinction-that-will-wipe-out-humans-and-all-mammals/">extinction events</a> in Earth’s history.&nbsp;</p>



<p>The research not only illuminates our understanding of past global changes but also issues a stark warning about the current fragility of marine ecosystems.</p>



<h2 class="wp-block-heading" id="h-triassic-jurassic-mass-extinction">Triassic–Jurassic mass extinction</h2>



<p>The study was focused on the Triassic–Jurassic mass extinction, which occurred approximately 200 million years ago. This event is among the Earth's major mass extinctions, periods characterized by significant global ecosystem collapses and widespread species extinctions.&nbsp;</p>



<p>Historically, these events have been closely associated with global environmental disturbances, frequently resulting in reduced oxygen levels (anoxia) in oceanic waters.</p>



<h2 class="wp-block-heading" id="h-focus-of-the-study">Focus of the study</h2>



<p>A common hypothesis has been that greater extents of ocean deoxygenation would naturally lead to larger scale extinctions. However, the current study challenges this assumption by demonstrating that the level of euxinia (an extreme form of deoxygenation) during the Triassic–Jurassic extinction was similar to what we observe today.</p>



<p>The research team, including experts from Royal Holloway (UK), <a href="https://www.tcd.ie/" target="_blank" rel="noreferrer noopener">Trinity College Dublin</a> (Ireland), and Utrecht University (Netherlands), analyzed chemical data extracted from ancient mudstone deposits in Northern Ireland and Germany.&nbsp;</p>



<h2 class="wp-block-heading" id="h-critical-insights-nbsp">Critical insights&nbsp;</h2>



<p>The results of the analysis highlight the role of anoxia in the marine extinctions during this period. The study also reveals a surprising limitation in the global extent of extreme deoxygenation at the time.</p>



<p>The experts found a correlation between increased extinction rates and spikes in deoxygenation across shallow marine environments along European continental margins.&nbsp;</p>



<h2 class="wp-block-heading" id="h-cautionary-tale-nbsp">Cautionary tale&nbsp;</h2>



<p>Upon further investigation, the team determined that the global extent of extreme deoxygenation was rather limited, and similar to the present day.&nbsp;</p>



<p>The research serves as a cautionary tale about the current state of our oceans, suggesting that they may be more vulnerable than previously thought.&nbsp;</p>



<p>The study of past global change events is invaluable in understanding the consequences of modern climate change, as well as in predicting and possibly mitigating future ecosystem tipping points.</p>



<h2 class="wp-block-heading" id="h-cascading-impacts">Cascading impacts</h2>



<p>“Scientists have long suspected that ocean deoxygenation plays an important role in the disturbance of marine ecosystems, which can lead to the extinction of species in marine environments," said study co-author Professor Micha Ruhl.</p>



<p>"The study of past time intervals of extreme environmental change indeed shows this to be the case, which teaches us important lessons about potential tipping points in local, as well as global ecosystems in response to climatic forcing."</p>



<p>“Crucially however, the current findings show that even when the global extent of deoxygenation is similar to the present day, the local development of anoxic conditions and subsequent locally increased extinction rates can cascade in widespread or global ecosystem collapse and extinctions, even in areas where deoxygenation did not occur."&nbsp;</p>



<h2 class="wp-block-heading" id="h-assessing-ecosystem-stability-nbsp">Assessing ecosystem stability&nbsp;</h2>



<p>Professor Ruhl said the research shows that global marine ecosystems become vulnerable, even when only local environments along the edges of the continents are disturbed.</p>



<p>"Understanding such processes is of paramount importance for assessing present day ecosystem stability, and associated food supply, especially in a world where marine deoxygenation is projected to significantly increase in response to global warming and increased nutrient run-off from continents.”</p>



<p>The study is published in the journal <a href="http://dx.doi.org/10.1038/s41561-023-01303-2" target="_blank" rel="noreferrer noopener"><em>Nature Geoscience</em></a></p>



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Today's ocean oxygen levels may have cascading impacts

Scientists have uncovered a crucial connection between ocean oxygen levels...

<p>A recent study led by <a href="https://wsu.edu/" target="_blank" rel="noreferrer noopener">Washington State University</a> reveals that the majority of <a href="https://www.earth.com/news/cannabis-use-strongly-linked-to-mental-disorders-in-a-new-study/">cannabis</a> users have stopped using conventional over-the-counter (OTC) or prescription sleep aids, favoring cannabis instead.&nbsp;</p>



<p>The study, which involved 1,255 cannabis users, found that more than 80% of participants no longer used traditional sleep aids like melatonin and benzodiazepines.&nbsp;</p>



<h2 class="wp-block-heading" id="h-fast-acting-and-effective-nbsp">Fast-acting and effective&nbsp;</h2>



<p>Cannabis users had a strong preference for inhaling high-THC marijuana by smoking joints or vaporizing flower. These methods are known to be fast-acting and effective in alleviating difficulties in falling asleep.</p>



<p>Interestingly, the researchers also found that about half of the respondents preferred cannabis strains containing both CBD and the terpene myrcene.&nbsp;</p>



<h2 class="wp-block-heading" id="h-benefits-of-myrcene-nbsp">Benefits of myrcene&nbsp;</h2>



<p>Myrcene, found in hops, basil, and other plants, is known for its potential sleep-promoting properties.&nbsp;</p>



<p>Study senior author Professor Carrie Cuttler noted that cannabis users seem to have independently discovered the benefits of myrcene for sleep.</p>



<p>“One of the findings that surprised me was the fact that people are seeking the terpene myrcene in cannabis to assist with sleep,” said Cuttler. “There is some evidence in the scientific literature to support that myrcene may help to promote sleep, so cannabis users seemed to have figured that out on their own.”</p>



<h2 class="wp-block-heading" id="h-key-insights">Key insights</h2>



<p>The research, conducted by Cuttler and psychology doctoral student Amanda Stueber, relied on self-reported data provided by Strainprint®, a Canada-based medical technology company.&nbsp;</p>



<p>The data revealed that cannabis users generally experienced more positive morning outcomes, such as feeling refreshed and focused, with fewer instances of headaches and nausea, compared to when they used traditional sleep aids.&nbsp;</p>



<p>However, cannabis users also reported feeling sleepier and experiencing mood changes, anxiety, dry mouth, and red eyes more frequently than with other sleep aids.</p>



<h2 class="wp-block-heading" id="h-cannabis-use-for-sleep">Cannabis use for sleep</h2>



<p>Cuttler pointed out that cannabis use for sleep was perceived as more advantageous than OTC medications or prescription sleep aids.&nbsp;</p>



<p>Unlike long-acting sedatives and alcohol, cannabis did not result in a "hangover" effect, though some lingering effects like sleepiness were reported.</p>



<h2 class="wp-block-heading" id="h-sleep-duration">Sleep duration</h2>



<p>The study further indicates that over 60% of participants achieved the recommended six to eight hours of sleep when using cannabis alone.&nbsp;</p>



<p>This is a stark contrast to the less than 20% who reported the same sleep duration while using a prescription or OTC sleep aid, or combining cannabis with such aids.&nbsp;</p>



<p>Only 33.8% of participants used cannabis edibles, and 14.1% opted for THC-containing capsules for sleep, possibly due to their delayed onset compared to inhalation methods.</p>



<h2 class="wp-block-heading" id="h-study-limitation">Study limitation</h2>



<p>Cuttler cautions that the study has limitations, including a strong selection bias towards individuals already using cannabis for perceived benefits.&nbsp;</p>



<p>“Not everyone is going to find that cannabis helps with their sleep and future research needs to employ more objective sleep measures to provide a more comprehensive understanding of the effects of cannabis for sleep,” said Cuttler.</p>



<p>The study is published in the journal <a href="http://dx.doi.org/10.37349/emed.2023.00171" target="_blank" rel="noreferrer noopener"><em>Exploration of Medicine</em></a><em>.</em></p>



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Most cannabis users no longer need conventional sleep aids

A recent study led by Washington State University reveals that...

<p>A study conducted by a collaborative team from Lancaster University, <a href="https://www.bangor.ac.uk/" target="_blank" rel="noreferrer noopener">Bangor University</a>, and the University of British Columbia sheds new light on the extensive benefits of secondary forests.&nbsp;</p>



<p>Naturally regrown forests, also known as secondary forests, play a critical role in the connectivity of old-growth forest <a href="https://www.earth.com/news/shrinking-koala-habitats-face-an-escalating-threat-of-bushfires/">habitats</a>. They can also help to shield other plants and wildlife from the harsh effects of climate change.&nbsp;</p>



<h2 class="wp-block-heading" id="h-forest-restoration-nbsp">Forest restoration&nbsp;</h2>



<p>"Restoration of forests across the globe would make a crucial contribution to achieving global climate change mitigation, with the growth of secondary forests on deforested land in the moist tropics fundamental to success," wrote the study authors.&nbsp;</p>



<p>"Although tropical secondary forests (defined here as forest growing on previously cleared land) store less carbon than old-growth forests, they rapidly remove carbon dioxide from the atmosphere."</p>



<h2 class="wp-block-heading" id="h-forest-fragmentation-nbsp">Forest fragmentation&nbsp;</h2>



<p>The research emphasizes the significant impact of secondary forests in mitigating the effects of forest fragmentation in the Amazon, an area crucial for global biodiversity conservation.&nbsp;</p>



<p>"Secondary forests cover just 190,000 km2 of the Amazon but connect more than 2 million isolated fragments of old-growth forest, prominent amongst the world’s most important habitats for biodiversity conservation," said study co-author Professor John Healey.</p>



<p>"The secondary forests are helping maintain connectivity for patches of old-growth forest that are too small to support long-term viable populations of rare species.”</p>



<p>These connections are vital for the survival of rare species that rely on extensive, undisturbed habitats.</p>



<h2 class="wp-block-heading" id="h-climate-buffering-nbsp">Climate buffering&nbsp;</h2>



<p>"Secondary forests are buffering as much as 41% of old-growth forest edges, potentially shielding them from negative edge effects such as hotter temperatures and wind," said study lead author Charlotte Smith.</p>



<p>"Proximity to old-growth forests can also help the rate of biodiversity and biomass recovery in secondary forests. It is positive that 94% of secondary forests were connected to old-growth forest. However, may old-growth forest remnants are small and degraded patches, so only 57% of secondary forest was connected to an area of extensive, structurally-intact old-growth.”</p>



<h2 class="wp-block-heading" id="h-study-implications">Study implications</h2>



<p>Professor Healey says the research provides powerful new evidence of the importance of managing forests at the landscape scale.&nbsp;</p>



<p>"Promoting forest restoration through secondary forests located next to old-growth forest remnants can play a vital role in both conserving biodiversity in these remnants and the rate of biodiversity recovery in the secondary forests themselves.”</p>



<p>The team notes that more research is needed to improve our understanding of the mechanisms driving variation in forest recovery and the potential benefits of secondary forest as buffers so that we can refine current estimates of forest carbon stocks and habitat provision.</p>



<h2 class="wp-block-heading" id="h-un-decade-on-ecosystem-restoration-nbsp">UN Decade on Ecosystem Restoration&nbsp;</h2>



<p>The study underscores the importance of secondary forests in the broader context of the climate crisis and the United Nations Decade on Ecosystem Restoration. This global initiative, spanning from 2021 to 2030, aims to halt the degradation of ecosystems and restore them to achieve global environmental goals.&nbsp;</p>



<p>Led by the United Nations Environment Programme (UNEP) and the Food and Agriculture Organization (FAO), the UN Decade on Ecosystem Restoration calls for a collective effort from governments, businesses, civil society, and individuals.</p>



<p>The primary objective is to revitalize millions of hectares of terrestrial and aquatic ecosystems. The restoration efforts encompass a wide range of ecosystems, including forests, farmlands, cities, wetlands, and oceans. These endeavors are crucial for combating climate change, enhancing food security, providing clean water, and halting biodiversity loss.</p>



<p>The study is published in the journal <a href="http://dx.doi.org/10.1088/1748-9326/ad039e" target="_blank" rel="noreferrer noopener"><em>Environmental Research Letters</em></a><em>.</em></p>



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Secondary forests reconnect fragmented habitats

A study conducted by a collaborative team from Lancaster University,...

<p>A new study led by Henry Häkkinen from the <a href="https://www.exeter.ac.uk/" target="_blank" rel="noreferrer noopener">University of Exeter</a> highlights a critical ecological issue. The researchers predict that naturalized <a href="https://www.earth.com/news/how-many-invasive-plant-species-are-in-the-world/">species</a>, those that are not native but have established themselves in new locations, possess the potential to spread even further into suitable habitats globally.&nbsp;</p>



<p>The study explores the dynamics of how naturalized species, including plants, birds, and mammals, have managed to extend their reach beyond their native regions.</p>



<h2 class="wp-block-heading" id="h-what-drives-species-invasions">What drives species invasions?</h2>



<p>"Understanding and predicting the spread of <a href="https://www.earth.com/news/economic-time-bomb-costs-of-invasive-species-are-greatly-underestimated/" target="_blank" rel="noreferrer noopener">introduced species</a> is one of the key conservation and ecological challenges of the 21st century," wrote the study authors.</p>



<p>"However, we know little about what causes the introduced range of some species to increase rapidly, while other species remain in small, isolated populations years after establishing self-sustaining populations."&nbsp;</p>



<p>"This major gap in our understanding prevents us from understanding how much of <a href="https://www.earth.com/earthpedia-articles/invasive-species-plants-animals/" target="_blank" rel="noreferrer noopener">invasive spread</a> is due to characteristics of the invader or the invaded environment." </p>



<h2 class="wp-block-heading" id="h-imminent-threat-of-naturalized-species">Imminent threat of naturalized species</h2>



<p>The researchers said the most imminent threat is posed by the many thousands of species that are naturalized outside their native range and may <a href="https://www.earth.com/news/biological-hazard-soil-on-sea-freight-loaded-with-invasive-species/" target="_blank" rel="noreferrer noopener">continue to spread</a> much more widely. "However, there is a surprising lack of attention paid to the potential spread of already-naturalized species." </p>



<p>"Without understanding what has affected the spread of these species historically, we can assess neither which species are likely to spread further nor the geographic regions that will be most affected."</p>



<p>Focusing on 833 naturalized plants, birds, and mammals, the researchers have identified the terrestrial areas most susceptible to future colonization by these species. Their findings highlight North America, Eastern Europe, and Australia as particularly vulnerable regions.&nbsp;</p>



<p>The study reveals a significant potential for the further spread of naturalized birds in North America, mammals in Eastern Europe, and plants in both these regions as well as in Australia.&nbsp;</p>



<h2 class="wp-block-heading" id="h-potential-spread-of-naturalized-species">Potential spread of naturalized species</h2>



<p>"The <a href="https://www.earth.com/news/unseen-crisis-37000-alien-species-have-been-introduced-by-human-activities/" target="_blank" rel="noreferrer noopener">potential spread</a> of naturalized species appears greatest in regions that are already heavily invaded, i.e., North America, Australia, and Europe. However, already-naturalized species also threaten areas of the world thought of as less invaded," wrote the study authors.</p>



<p>"In South America and Southern Africa around 200 regionally naturalized plants have the potential to spread widely - a number comparable to that in Australia and China, which have historically borne the brunt of biological invasions."</p>



<p>"Nonetheless, the potential for regionally naturalized species to spread in sub-Saharan Africa and the north of South America is lower than one would expect from the globally high numbers of species naturalized there. This is potentially encouraging given the recent increases in regional trade and transportation infrastructure in these regions that could increasingly facilitate the spread of naturalized species."</p>



<h2 class="wp-block-heading" id="h-delay-in-expansion-nbsp">Delay in expansion&nbsp;</h2>



<p>Despite having ample opportunities to expand, many of these species have not yet colonized all areas with a compatible climate. This delay in expansion suggests that some introduced species may not become problematic immediately but could pose risks after a lag period.</p>



<p>"Nearly all species we studied have yet to expand throughout most of the areas that are climatically suitable for them, within the biogeographic regions where they have naturalized. This is despite substantial time to invade: 25% have been established for over 150 years," noted the researchers.</p>



<h2 class="wp-block-heading" id="h-invasional-meltdown">Invasional meltdown</h2>



<p>The experts also identified the key factors influencing the spread of naturalized species. They found that a species' introduction history, its dispersal capabilities, and the presence of suitable habitats are more critical in determining its spread than its preferred habitat or interactions with local species. This insight is vital for understanding and predicting the movement of non-native species.</p>



<p>A concerning finding of the study is the concept of "invasional meltdown." This phenomenon occurs when multiple introduced species collectively amplify their impact and ability to establish themselves in a new environment, potentially leading to devastating ecological consequences.&nbsp;</p>



<p>While many of the species that were studied have a minimal impact on their own, their collective effect could be significantly more harmful.</p>



<h2 class="wp-block-heading" id="h-future-implications-of-naturalized-species">Future implications of naturalized species</h2>



<p>“Species invasions can devastate biodiversity, agriculture, and livelihoods, so it’s worrying that so many naturalized species seem poised to spread further," wrote the researchers.</p>



<p>"But there is a glimmer of hope that invasions are much more limited than they could be – ecosystems may be holding off invaders better than we expected, and good management could help stem the spread.”</p>



<p>The study is published in the journal <a href="http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002361" target="_blank" rel="noreferrer noopener"><em>PLoS Biology</em></a>.</p>



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Invasive naturalized species will continue to spread globally

A new study led by Henry Häkkinen from the University...

White,Summer,Daisies,Reaching,Towards,Blue,Sky

<p>In a remarkable fusion of biology and engineering, the team led by Prof Christian Fankhauser at the <a href="https://www.unil.ch/central/en/home.html" target="_blank" rel="noreferrer noopener">University of Lausanne</a> (UNIL), in collaboration with <a href="https://www.epfl.ch/en/" target="_blank" rel="noreferrer noopener">EPFL</a>, has made a significant breakthrough in understanding how plants perceive light. </p>



<p>This study reveals how plants, devoid of visual organs, determine the source of light using the unique optical properties at the air-water interface within their tissues.</p>



<h2 class="wp-block-heading" id="h-phototropism-in-plants">Phototropism in plants</h2>



<p>Phototropism, the orientation of <a href="https://www.earth.com/news/scientists-talk-to-plants-using-light-based-messaging/" target="_blank" rel="noreferrer noopener">plants</a> towards light, is a critical phenomenon for their survival. As Prof Fankhauser explains, "The majority of living organisms (micro-organisms, plants and animals) have the ability to determine the origin of a <a href="https://www.earth.com/news/study-reveals-why-plants-have-a-burst-of-activity-at-dawn/" target="_blank" rel="noreferrer noopener">light source</a>, even in the absence of a sight organ comparable to the eye." </p>



<p>This ability is crucial for plants to optimally position their organs for maximum <a href="https://www.earth.com/news/artificial-light-affects-seasonal-rhythms-of-plants-in-the-us/" target="_blank" rel="noreferrer noopener">sunlight exposure</a>, facilitating efficient <a href="https://www.earth.com/news/key-to-life-on-earth-photosynthesis-begins-on-the-quantum-level-with-a-single-photon/" target="_blank" rel="noreferrer noopener">photosynthesis</a>, the process by which they convert light energy into chemical energy.</p>



<h2 class="wp-block-heading" id="h-light-detection-mechanism">Light detection mechanism</h2>



<p>The key to this discovery was the observation of a mutant variety of <em>Arabidopsis thaliana</em>, a model plant species, with a uniquely transparent stem. Prof Fankhauser's team, in conjunction with DrSc. Andreas Schüler and the UNIL's Electron Microscopy Centre, found that the normal, milky appearance of plant stems is due to air-filled channels in their tissues. </p>



<p>In contrast, the mutant plants had these channels filled with water, giving them a translucent appearance. These channels, it turns out, are crucial for establishing a <a href="https://www.earth.com/news/scientists-can-control-plants-using-nothing-but-light/" target="_blank" rel="noreferrer noopener">light gradient</a> within the plant, a mechanism previously unknown.</p>



<p>Martina Legris, a postdoctoral fellow in Prof Fankhauser's group, sheds light on the underlying science. She clarifies, “More specifically, air and water have different refractive indices. This leads to light scattering as it passes through the seedling." </p>



<p>This scattering of light, akin to the formation of rainbows, enables the plant to 'read' the light gradient and determine the light source's direction.</p>



<h2 class="wp-block-heading" id="h-broader-implications-of-phototropism">Broader implications of phototropism</h2>



<p>This fascinating research elucidates a novel mechanism for <a href="https://www.earth.com/news/light-and-temperature-collaborate-to-boost-plant-growth/" target="_blank" rel="noreferrer noopener">light perception</a> in plants, and also provides insights into the formation and functions of air-filled intercellular channels. These channels are known to aid in gas exchange and offer resistance to hypoxia during flooding. </p>



<p>Understanding their development from embryonic stages to adulthood remains an area ripe for exploration. The genetic resources utilized in this study promise to further our understanding of these intricate structures.</p>



<p>In summary, the collaborative efforts of UNIL and EPFL have unveiled a fascinating aspect of plant biology, opening new avenues in our understanding of plant physiology and their interaction with the environment. This study not only enriches our scientific knowledge but also underscores the importance of interdisciplinary research in unraveling the complexities of nature.</p>



<p>The full study was published in the journal <em><a href="https://www.science.org/doi/10.1126/science.adh9384" target="_blank" rel="noreferrer noopener">Science</a></em>.</p>



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Ingredients,For,Mediterranean,Diet

<p>A new study published in the journal <a href="http://dx.doi.org/10.1002/mnfr.202300271" target="_blank" rel="noreferrer noopener"><em>Molecular Nutrition and Food Research</em></a> highlights the beneficial impact of a Mediterranean diet on the <a href="https://www.earth.com/news/cheese-may-contain-nutrients-that-prevent-cognitive-decline/">cognitive health</a> of older adults.&nbsp;</p>



<p>The extensive research, led by Mireia Urpí-Sardá, explores the biological mechanisms underlying the diet's positive effects on the aging brain.</p>



<p>The study is part of the European "Joint Programming Initiative - A Healthy Diet for a Healthy Life" (<a href="https://www.healthydietforhealthylife.eu/" target="_blank" rel="noreferrer noopener">JPI HDHL</a>) and spans twelve years. The research involved 840 participants over the age of 65, predominantly women, from the Bourdeaux and Dijon regions of France.</p>



<h2 class="wp-block-heading" id="h-dietary-metabolomic-index-nbsp">Dietary metabolomic index&nbsp;</h2>



<p>"Within the framework of the study, a dietary metabolomic index has been designed - based on biomarkers obtained from the participants’ serum - on the food groups that form part of the <a href="https://www.earth.com/news/mediterranean-lifestyle-linked-to-a-30-percent-lower-risk-of-death/" target="_blank" rel="noreferrer noopener">Mediterranean</a> diet. Once this index is known, its association with cognitive impairment is evaluated," explained study co-author Cristina Andrés-Lacueva, a professor at the <a href="https://web.ub.edu/en/" target="_blank" rel="noreferrer noopener">University of Barcelona</a>.</p>



<h2 class="wp-block-heading" id="h-mediterranean-diet-and-key-biomarkers">Mediterranean diet and key biomarkers </h2>



<p>Key biomarkers in this study include levels of saturated and unsaturated fatty acids, gut microbiota-derived polyphenol metabolites, and other phytochemicals.&nbsp;</p>



<p>Some of these indicators have been recognized as marks of exposure to the main food groups of the <a href="https://www.earth.com/news/pollution-in-the-mediterranean-sea-is-an-urgent-issue/" target="_blank" rel="noreferrer noopener">Mediterranean</a> diet, and may also be responsible for the health benefits of this dietary pattern.</p>



<p>The biomarkers are part of a larger set called the metabolome, which is the complete set of small-molecule chemicals found within a biological sample.&nbsp;</p>



<p>Among participants who were not suffering from cognitive decline at the start of the study, the metabolome was analyzed through serum samples.</p>



<p>Over the twelve-year period, cognitive impairment was evaluated using five different neuropsychological tests.&nbsp;</p>



<p>The results revealed a clear protective link between high scores on the <a href="https://www.earth.com/news/mediterranean-diet-can-lead-to-longer-life/" target="_blank" rel="noreferrer noopener">Mediterranean</a> diet serum biomarker index and reduced cognitive decline in older individuals.</p>



<h2 class="wp-block-heading" id="h-significance-of-the-mediterranean-diet">Significance of the Mediterranean diet</h2>



<p>Mercè Pallàs, a professor at the <a href="http://www.neurociencies.ub.edu/" target="_blank" rel="noreferrer noopener">UB Neurosciences Institute</a> (UBneuro), emphasized the significance of the team's approach.</p>



<p>"The use of dietary pattern indices based on food-intake biomarkers is a step forward towards the use of more accurate and objective dietary assessment methodologies that take into account important factors such as bioavailability," said Pallàs.</p>



<p>"We found that adherence to <a href="https://www.earth.com/news/mediterranean-diet-helps-offset-the-health-impacts-of-obesity/" target="_blank" rel="noreferrer noopener">Mediterranean</a> diet assessed by a panel of dietary biomarkers is inversely associated with long-term cognitive decline in older people," noted study lead author Alba Tor-Roca.</p>



<p>"These results support the use of these indicators in long-term follow-up assessments to observe the health benefits associated with the Mediterranean diet or other dietary patterns and therefore, guide personalized counseling at older ages."</p>



<h2 class="wp-block-heading" id="h-mediterranean-diet-nbsp">Mediterranean diet&nbsp;</h2>



<p>The <a href="https://www.earth.com/news/mediterranean-diet-reduces-the-risk-of-dementia/" target="_blank" rel="noreferrer noopener">Mediterranean</a> diet, inspired by the traditional eating habits of countries bordering the Mediterranean Sea, is renowned for its numerous health benefits, particularly in promoting heart health and reducing the risk of chronic diseases. </p>



<p>This diet emphasizes the consumption of plant-based foods, including fruits, vegetables, whole grains, nuts, and seeds. Olive oil is a key component, serving as the primary source of added fat, renowned for its heart-healthy properties.</p>



<h3 class="wp-block-heading" id="h-key-features-of-the-mediterranean-diet">Key features of the Mediterranean diet</h3>



<p>One of the main features of the Mediterranean diet is its emphasis on fresh, whole foods and minimal processing. Fruits and vegetables are consumed in abundance, providing a rich source of vitamins, minerals, and antioxidants.&nbsp;</p>



<p>Whole grains, like whole wheat, oats, barley, and brown rice, are preferred over refined grains, offering more fiber and nutrients.</p>



<h3 class="wp-block-heading" id="h-protein-sources-nbsp">Protein sources&nbsp;</h3>



<p>Protein sources in the Mediterranean diet are primarily plant-based, with legumes such as beans, lentils, and chickpeas playing a significant role.&nbsp;</p>



<p>Fish and seafood are also important, recommended at least twice a week, providing heart-healthy omega-3 fatty acids. Poultry, eggs, cheese, and yogurt are consumed in moderate amounts, while red meats and sweets are limited.</p>



<h3 class="wp-block-heading" id="h-mediterranean-diet-social-aspects">Mediterranean diet social aspects</h3>



<p>Another distinctive aspect of this diet is its social and lifestyle components. Meals are often enjoyed in a communal setting, encouraging slower eating and the enjoyment of food as part of a social experience. Moderate consumption of red wine is also a feature, usually enjoyed with meals.</p>



<p>Overall, the Mediterranean diet is not just about food choices but also about a healthier and more holistic lifestyle, emphasizing plant-based foods, healthy fats, moderate protein from lean sources, and an enjoyable eating experience.</p>



<h2 class="wp-block-heading" id="h-health-benefits-of-the-mediterranean-diet">Health benefits of the Mediterranean diet</h2>



<p>The Mediterranean diet offers a multitude of health benefits, making it one of the most recommended eating patterns by health professionals worldwide.&nbsp;</p>



<h3 class="wp-block-heading" id="h-heart-health">Heart health</h3>



<p>At its core, this diet is heart-healthy, significantly reducing the risk of cardiovascular diseases. The high intake of olive oil, nuts, and fish, which are rich in healthy fats, particularly omega-3 fatty acids, contributes to lower cholesterol levels and improved heart health.</p>



<h3 class="wp-block-heading" id="h-weight-management-nbsp">Weight management&nbsp;</h3>



<p>Moreover, this diet is beneficial for weight management. The emphasis on whole, nutrient-dense foods, along with healthy fats and fiber from fruits, vegetables, and whole grains, helps in maintaining a healthy weight and can aid in weight loss.&nbsp;</p>



<p>The high fiber content also contributes to better digestive health and can help prevent constipation and other digestive issues.</p>



<h3 class="wp-block-heading" id="h-diabetes">Diabetes</h3>



<p>Another significant advantage of the Mediterranean diet is its role in reducing the risk of type 2 diabetes. The diet’s low glycemic index foods help in stabilizing blood sugar levels.&nbsp;</p>



<h3 class="wp-block-heading" id="h-inflammation">Inflammation</h3>



<p>Additionally, its anti-inflammatory properties, primarily due to antioxidants found in fruits and vegetables, olive oil, and nuts, can reduce the risk of chronic diseases linked to inflammation, including certain types of cancer.</p>



<h3 class="wp-block-heading" id="h-cognitive-health">Cognitive health</h3>



<p>The diet also has a positive impact on cognitive health. Studies have shown that it may lower the risk of Alzheimer's disease and other forms of dementia, possibly due to the combination of healthy fats and high levels of antioxidants.</p>



<h3 class="wp-block-heading" id="h-longevity">Longevity</h3>



<p>The Mediterranean diet promotes longevity and overall well-being. The combination of nutrient-rich foods, healthy fats, and a lifestyle that emphasizes social eating and moderate physical activity contributes to a longer and healthier life.</p>



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Food for the aging brain: Mediterranean diet protects cognitive health

A new study published in the journal Molecular Nutrition and...

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