Targeting cells that cause cancer and aging
Today’s Video of the Day from the USC Viterbi School of Engineering describes new research that may ultimately lead to the development of treatments to target cells that cause cancer and aging.
“To drink from the fountain of youth, you have to figure out where the fountain of youth is, and understand what the fountain of youth is doing,” said study co-author Professor Nick Graham. “We’re doing the opposite; we’re trying to study the reasons cells age, so that we might be able to design treatments for better aging.”
The research is focused on senescence, the process in which cells permanently stop creating new cells, which is one of the key causes of age-related decline and disease.
“Senescent cells are effectively the opposite of stem cells, which have an unlimited potential for self-renewal or division,” said study lead author Alireza Delfarah. “Senescent cells can never divide again. It’s an irreversible state of cell cycle arrest.”
The study is published in the Journal of Biological Chemistry.
Video Credit: Dennis Lee, USC Viterbi School of Engineering