Anti-aging effects of dietary restriction are mediated by a protein

While it is known that reduced food intake can boost health and longevity, the molecular mechanisms involved remain a mystery. In a study of fruit flies, researchers at the Max Planck Institute have now identified a protein named Sestrin that mediates the beneficial, anti-aging effects of dietary restriction. The experts found that increasing the amount of Sestrin in fruit flies not only extended their lifespan, but also protected the flies against the unfavorable effects of a protein-rich diet. Furthermore, the researchers demonstrated that Sestrin improved the …