A new study may explain why a night of binge drinking often gives people the munchies. A team of researchers at Pennsylvania State University College of Medicine has found that junk food cravings and heavy drinking are controlled by the same brain circuit.
“Obesity and alcoholism, two of the most common chronic disorders in the United States, may be behaviorally linked as binge intake of palatable diets, such as diets high in fat, and binge alcohol intake may utilize the same neurocircuitry,” wrote the researchers.
The theory is consistent with previous research which found that the consumption of alcohol affects the same regions of the brain that control overeating. The current study was focused on the eating and drinking patterns of three groups of early adult male mice.
One group of mice had unlimited access to a high-fat diet and limited access to a beverage containing water mixed with alcohol, while a second group had a normal rodent diet and the same limited access to the alcoholic beverage. The third test group of mice was given a “binge diet,” with limited access to both a high-fat diet and the alcoholic beverage.
The ratio of alcohol to drinking water was incrementally increased from 10 to 20 percent over the course of eight weeks. The mice also had unlimited access to drinking water throughout the experiment.
The binge diet group gained and lost weight based on their eating cycles. These mice also drank more alcohol than water during their access period, showing a clear preference for alcohol. Both of the other groups drank less alcohol than the binge diet group.
According to the researchers, the findings indicate that limiting access to foods high in fat promotes binge-like eating patterns, which subsequently activates the brain to binge on alcohol.
“Given the increasing rates of binge drinking and overall obesity rates in the U.S. in recent years, we think this new mouse model will be of critical importance in the near future,” said study first author Caitlin Coker.
The research was presented at the American Physiological Society’s annual meeting Experimental Biology 2019.
—
By Chrissy Sexton, Earth.com Staff Writer