For years, bacteria dominated gut health research. Now, the gut virome is gaining attention as a major player in health and disease. Bacteriophages, which are viruses that infect <a href="https://www.earth.com/news/scientists-think-they-found-two-key-bacteria-that-cause-multiple-sclerosis/">bacteria</a>, make up around 90% of the gut virome.



Though small in biomass, they outnumber bacteria by up to tenfold. These tiny viruses shape microbial communities, influence immunity, and affect gut health.



A landmark review published recently in Precision Clinical Medicine reveals how the gut virome links to diseases like inflammatory bowel disease (<a href="https://www.cdc.gov/inflammatory-bowel-disease/about/index.html" target="_blank" rel="noreferrer noopener">IBD</a>), <a href="https://www.earth.com/news/colonoscopy-vs-stool-tests-doctors-found-out-which-is-better-at-detecting-cancer/">colorectal cancer</a>, and Clostridium difficile infection (<a href="https://my.clevelandclinic.org/health/diseases/15548-c-diff-infection" target="_blank" rel="noreferrer noopener">CDI</a>).



<h2 class="wp-block-heading" id="h-gut-s-virome-changes-across-life-stages">Gut's virome changes across life stages</h2>



The gut virome changes constantly throughout life. Infants show high <a href="https://www.earth.com/news/bacteria-that-eat-forever-chemicals-discovered-in-contaminated-soil/">diversity</a> in gut bacteriophages (also called phages), which is shaped by birth method, diet, and antibiotic exposure.



As individuals grow, diet and hormones refine the virome. In adults, phages and bacteria form a stable, <a href="https://www.nature.com/articles/s41579-021-00536-5" target="_blank" rel="noreferrer noopener">balanced community</a>.



However, aging shifts this balance. Older adults show more lysogenic phages, which integrate into bacterial genomes and potentially alter metabolism and immune interactions.



<h2 class="wp-block-heading" id="h-diet-and-environment-shape-the-virome">Diet and environment shape the virome</h2>



Diet greatly <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9455721/" target="_blank" rel="noreferrer noopener">influences</a> the virome. High-fiber diets support beneficial phages by encouraging helpful bacteria. Western diets, rich in fat and sugar, promote harmful <a href="https://www.earth.com/news/some-bacteria-breathe-by-creating-electricity/">phages</a>.



Urbanization reduces exposure to natural viruses. Studies show that rural diets which are rich in fiber boost gut virome diversity.



Host genetics and immunity also play roles. Genetic variants can affect viral detection and clearance. Immune defenses, like <a href="https://my.clevelandclinic.org/health/treatments/interferons" target="_blank" rel="noreferrer noopener">interferons</a> and <a href="https://www.immunology.org/public-information/bitesized-immunology/receptors-molecules/immunoglobulin-iga" target="_blank" rel="noreferrer noopener">IgA</a>, keep the virome balanced.



However, immune dysfunction can trigger viral imbalances, worsening conditions like HIV and gut inflammation.



<h2 class="wp-block-heading" id="h-viruses-and-bacteria-interacting">Viruses and bacteria interacting</h2>



Viruses, including phages, along with bacteria and fungi form a complex and dynamic ecosystem in the gut. The components interact in positive and negative ways, thus affecting host metabolism, immune regulation and resistance to disease. 



The gut virome plays a crucial regulatory role in these intricate interactions. Phages interact with bacteria through lytic, lysogenic, and budding cycles, which regulate bacterial populations and gene flow. 



In a form of microbial arms race, the bacteria defend against phages using <a href="https://www.earth.com/news/crispr-used-to-remove-extra-chromosomes-in-down-syndrome-and-restore-cell-function/">CRISPR systems</a> and the phages evolve escape mechanisms.



Some phages even boost bacterial metabolism and biofilm formation, affecting disease risk. For instance, phages can transfer genes that enhance bacterial survival in acidic conditions.



<h2 class="wp-block-heading" id="h-virome-s-influence-on-immunity">Virome’s influence on immunity</h2>



The virome affects gut immunity deeply. <a href="https://www.earth.com/news/when-bacteria-get-hungry-they-turn-on-each-other/">Phages</a> can anchor to gut mucus and form a protective barrier. They also shape our own <a href="https://www.ncbi.nlm.nih.gov/books/NBK459471/" target="_blank" rel="noreferrer noopener">T and B cell</a> activity and regulate macrophages. In addition, viruses that infect eukaryotic cells affect immune pathways and maintain gut balance.



<figure class="wp-block-image aligncenter size-full"><a href="https://www.earth.com/wp-content/uploads/2025/07/virome_microbiome_human-gut_graphic_credit-PCM_1m.jpg"><img src="https://www.earth.com/wp-content/uploads/2025/07/virome_microbiome_human-gut_graphic_credit-PCM_1s.webp" alt="This infographic illustrates four major therapeutic approaches—fecal microbial transplantation (FMT), phage therapy, dietary interventions, and probiotics/prebiotics—that aim to restore gut health by modulating the microbiome and virome. Each strategy offers unique methods, benefits, and challenges in managing gastrointestinal disorders such as IBD, CRC, and CDI, highlighting the growing potential of virome-informed precision medicine. Credit: Precision Clinical Medicine" class="wp-image-1976450"/></a><figcaption class="wp-element-caption">This infographic illustrates four major therapeutic approaches—fecal microbial transplantation (FMT), phage therapy, dietary interventions, and probiotics/prebiotics—that aim to restore gut health by modulating the microbiome and virome. Each strategy offers unique methods, benefits, and challenges in managing gastrointestinal disorders such as IBD, CRC, and CDI, highlighting the growing potential of virome-informed precision medicine. Click image to enlarge. Credit: Precision Clinical Medicine</figcaption></figure>



However, infections and antibiotics can disrupt this harmony and lead to inflammation. Phages can trigger TLR9 pathways, causing excessive immune responses such as those linked to IBD.



<h2 class="wp-block-heading" id="h-virome-s-role-in-disease">Virome’s role in disease</h2>



Imbalances in the gut virome have been linked to several gut diseases. In IBD, specific phages become abundant and worsen inflammation.



Certain groups of phages (such as Caudovirales) amplify immune responses, while norovirus and rotavirus can damage the gut lining. Viral imbalances are also common in IBS and CDI.



In colorectal cancer, phages and eukaryotic viruses like HPV and JC virus (polyomavirus) appear more often. They may promote tumor growth by altering bacterial communities and gene expression.



Studies suggest that some phages directly influence cancer risk by promoting biofilms and transferring harmful genes.



<h2 class="wp-block-heading" id="h-virus-based-treatments">Virus-based treatments</h2>



Several therapies now explore the virome’s potential to treat certain diseases or conditions. Fecal microbiota transplantation (FMT) restores gut balance and reduces inflammation in IBD and CDI.



FMT works not only by shifting bacteria but also by transferring beneficial phages. Studies show that donor phages often align quickly with recipients and promote recovery.



Phage therapy, which uses viruses to kill specific bacteria, is another approach that is gaining traction. It can reduce harmful microbes while preserving beneficial ones.



Researchers have created phage cocktails that target specific gut pathogens like E. coli and Klebsiella pneumoniae, and this approach has had promising results in animal models.



<h2 class="wp-block-heading" id="h-diet-as-a-tool-to-reshape-the-virome">Diet as a tool to reshape the virome</h2>



Dietary strategies also reshape the virome. High-fiber diets boost beneficial phages and support bacterial diversity.



Whey protein has shown potential in managing Crohn’s disease by improving phage-bacteria interactions.



Other interventions, such as exclusive enteral nutrition and low-FODMAP diets, also show benefits in gut diseases.



<h2 class="wp-block-heading" id="h-probiotics-prebiotics-and-phages">Probiotics, prebiotics, and phages</h2>



Probiotics introduce beneficial bacteria, while prebiotics feed them. Combining them, known as symbiotics, shows promise for restoring and maintaining gut health.



Recent research suggests that adding phages can enhance these effects. Phage-based products, such as PreforPro, have already shown benefits in clinical trials.



These products can reduce populations of harmful bacteria and improve probiotic performance, thereby creating a more stable gut environment.



<h2 class="wp-block-heading" id="h-using-gut-viruses-to-detect-diseases-early">Using gut viruses to detect diseases early</h2>



The gut virome is now being studied as a diagnostic tool. Viral patterns are more stable than bacterial ones, making them reliable biomarkers.



Distinct virome signatures can predict IBD and colorectal cancer. Machine learning models already use virome data to detect these diseases early.



Virome profiling may also track treatment responses, such as FMT success in IBD and CDI.



<h2 class="wp-block-heading" id="h-challenges-and-future-prospects">Challenges and future prospects</h2>



Despite the excitement over potential new treatments, many hurdles remain. Current methods struggle to capture the full virome due to technical limits.



Many phages are still unculturable, and their roles remain unclear. Researchers are working to improve viral databases and develop targeted therapies. Once these gaps close, virome-based therapies could change how we treat gut diseases.



The study is published in the journal <a href="https://academic.oup.com/pcm/article/8/2/pbaf010/8152264" target="_blank" rel="noreferrer noopener">Precision Clinical Medicine</a>.



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Move over microbiome, it's time for the human gut's 'virome' to shine

For years, bacteria dominated gut health research. Now, the gut virome is gaining attention as a major player in health and disease. Bacteriophages, which are viruses that infect bacteria, make up around 90% of the gut virome. Though small in biomass, they outnumber bacteria by up to tenfold. These tiny viruses shape microbial communities, influence immunity, and affect gut health. A landmark review published recently in Precision Clinical Medicine reveals how the gut virome links to diseases like inflammatory bowel disease (IBD), colorectal cancer, and Clostridium difficile infection (CDI)....

A team of neuroscientists at the <a href="http://www.mit.edu/">Massachusetts Institute of Technology</a> (MIT) has discovered a way that the brain compensates during challenges when it doubts its own abilities. The study revealed that when tasks are too complicated, the <a href="http://www.earth.com/news/brain-control-movement-limbs/">brain</a> draws on previous experiences for guidance. According to the experts, this strategy actually improves overall performance.

Study senior author Mehrdad Jazayeri is the Robert A. Swanson Career Development Professor of Life Sciences and a member of MIT's <a href="https://mcgovern.mit.edu/mcgovern-institute-for-brain-research-at-mit">McGovern Institute for Brain Research</a>.

“If you're doing something that requires a harder mental transformation, and therefore creates more uncertainty and more variability, you rely on your prior beliefs and bias yourself toward what you know how to do well, in order to compensate for that variability,” explained Professor Jazayeri.

For many decades, neuroscientists have recognized an amount of uncertainty in the brain as it responds to things that we see or hear but do not fully understand. This uncertainty causes random fluctuations of electrical activity in the brain, or “noise,” that is also generated during social interactions and as we attempt to recall past events.

Previous research has revealed many strategies which help the brain to compensate for this uncertainty, such as relying on an average of its past experiences. The brain is also known to handle conflicting evidence by choosing the more reliable source.

Professor Jazayeri explained that these strategies have been previously shown to work together to increase bias toward a particular outcome, which makes our overall performance better because it reduces variability.

Noise is also produced in the brain during the mental conversion of sensory information into a motor plan. For example, if you try to write your name backward so that it can be read in the mirror, the brain faces uncertainty when attempting to perform this unfamiliar conversion.

Researchers set out to investigate the brain's response to this type of mental conversion using three different tasks. For each task, they compared the performance of the participants in a version of the task that was simple versus a version that was extra challenging.


Overall, the experts found that during the version of a task that required difficult mental transformations, people altered their performance using the same strategies that they use to overcome noise in sensory perception. For example, when the individuals  had to draw lines ranging from 7.5 to 15 centimeters, they tended to draw lines that were closer to the average length of all the lines they had previously drawn. 

“This regression to the mean is a very common strategy for making performance better when there is uncertainty,” said Professor Jazayeri.

Based on their findings, the researchers believe that when people get very good at a task that requires complex computation, the noise will decrease and become less detrimental to overall performance. At this point, people will trust their computations more and stop relying on averages.

“As it gets easier, our prediction is the bias will go away, because that computation is no longer a noisy computation,” said Professor Jazayeri. “You believe in the computation; you know the computation is working well.”

The study is published in the journal <a href="https://www.nature.com/ncomms/">Nature Communications</a>.

--

By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

How the brain compensates for its own uncertainty

A team of neuroscientists at the Massachusetts Institute of Technology...

Could Fido’s coat color play a role in his health? In the case of chocolate Labs, a new study shows that it might. 

Researchers at the <a href="https://sydney.edu.au/">University of Sydney</a> have analyzed vet records for 33,000 Labrador retrievers of all colors. They found that chocolate Labs have higher rates of ear and skin infections than black and yellow Labs do. 

They also found that chocolate Labs’ lifespans are, on average, 10 percent shorter than their non-chocolate counterparts. Lead author Dr. Paul McGreevy said the researchers were surprised by the findings.

"The relationships between coat color and disease may reflect an inadvertent consequence of breeding certain pigmentations," he said. "Because chocolate color is recessive in dogs, the gene for this color must be present in both parents for their puppies to be chocolate. Breeders targeting this color may therefore be more likely to breed only Labradors carrying the chocolate coat gene. It may be that the resulting reduced gene pool includes a higher proportion of genes conducive to ear and skin conditions."

They found that across the UK, the most common health conditions among chocolate Labs were obesity, ear infections and joint problems. Male dogs who had been neutered were more prone to obesity than other Labs.

"We found that 8.8 percent of UK Labradors are overweight or obese, one of the highest percentages among dog breeds in the VetCompass database," McGreevy said.

The researchers collected their data through the VetCompass Programme, which began in 2007 at the <a href="https://www.rvc.ac.uk/">Royal Veterinary College</a> in London in partnership with the University of Sydney. 

The program is now working to collect data on chocolate Labs and their black and yellow fellows in Australia. VetCompass now works with all of Australia's veterinary schools with support from the <a href="https://www.arc.gov.au/">Australian Research Council</a>.

The study has been published in the open source journal <a href="https://cgejournal.biomedcentral.com/">Canine Genetics and Epidemiology</a>.

Chocolate Labs coat colors could affect health

Could Fido’s coat color play a role in his health?...

Scientists finally have solid evidence: the Earth’s core is solid, if a little squishy, a new study has discovered.

The theory that Earth’s core is solid dates back to 1936, proposed by seismologist Inge Lehmann as she reanalyzed data from the massive 1929 Murchison, New Zealand earthquake. But until recently, there was no way to prove it. 

Then the team from <a href="http://www.anu.edu.au/">Australia National University</a> struck on the idea of using earthquakes again. They decided to study echoes of earthquakes using a technique that researchers have been using to measure Antarctic ice sheets for decades.

Dr. Hrvoje Tkalčić, scholar Than-Son Phạm and their colleagues looked at similarities recorded by pairs of receivers after major earthquakes. The team detected “J waves,” which can only pass through solid objects, deep in the Earth’s core. 

“Using a global network of stations, we take every single receiver pair and every single large earthquake – that’s many combinations – and we measure the similarity between the seismograms,” Tkalčić told the magazine <a href="https://www.newsweek.com/">Newsweek</a>. “That’s called cross-correlation, or the measure of similarity. From those similarities we construct a global correlogram – a sort of fingerprint of the Earth.”

What that fingerprint showed was that there is solid material in the Earth’s core. However, it’s also a lot softer than scientists expected. 

“It turns out – if our results are correct – the inner core shares some similar elastic properties with gold and platinum,” Tkalčić said. “The inner core is like a time capsule; if we understand it we’ll understand how the planet was formed, and how it evolves.”

The study solves one of the mysteries about Earth’s core, Tkalčić and Pham said, but there is still research to be done before scientists come close to understanding the center of our planet.

“For instance, we don’t know yet what the exact temperature of the inner core is, what the age of the inner core is, or how quickly it solidifies, but with these new advances in global seismology, we are slowly getting there,” Tkalčić said.

The study has been published in the journal <a href="https://www.sciencemag.org/">Science</a>.

Earthquake 'echoes' show Earth's core is solid

Scientists finally have solid evidence: the Earth’s core is solid,...

Carrot extract could be the key to creating environmentally friendly cement, according to a new study by British researchers.

The team at <a href="http://www.lancaster.ac.uk/">Lancaster University</a> used a surprisingly low-tech method to test their theory that carrot extract could make cement stronger while cutting carbon dioxide emissions: a common household blender.

The scientists blended nano platelets extracted from carrots and ordinary cement to create a crack-resistant material up to 80 percent stronger than traditional cement.

“The composites are not only superior to current cement products in terms of mechanical and microstructure properties, but also use smaller amounts of cement,” Dr. Mohamed Saai told the <a href="https://www.dailymail.co.uk/home/index.html">Daily Mail</a>. “This significantly reduces both the energy consumption and [carbon dioxide] emissions associated with cement manufacturing.”

The key is in the cellulose.

The fibrous material is what makes carrots so rigid and crunchy, even though the root vegetables are mostly water, Christian Kemp-Griffin, CEO of Scotland-based CelluComp, the company that provided the carrot extract.

“Those fibers have strength characteristics in them. It’s the building blocks of the strength of a vegetable,” he told <a href="https://www.reuters.com/">Reuters</a>.

It can be extracted from other plant material, but vegetables are easiest, Kemp-Griffin said. 

Adding the carrot extract saved about 88 pounds of cement per cubic square meter of concrete, and about the same amount in carbon dioxide emissions, the Lancaster researchers discovered during proof-of-concept studies.

“Our preliminary results show that adding about half a kilogram of carrot nanomaterial will reduce about 10 kilograms of cement per one cubic meter of concrete,” Saafi told the Mail.

The news could be big for the construction industry, not just because the resulting material seems stronger and less likely to crack. According to the <a href="https://www.iea.org/">International Energy Agency</a>, cement produces about seven percent of global carbon dioxide emissions.

Carrot extract isn’t the only solution, either. The British researchers are also experimenting with cellulose extracted from sugar beets.

Carrot extract could make cement stronger, more eco-friendly

Carrot extract could be the key to creating environmentally friendly...

The Pacific blob is back, and that could spell bad news for the west coasts of the United States and Canada.

That’s because in the past, the blob of warm ocean water has brought with it poor feeding for salmon. It’s been connected to whale deaths and warmer temperatures in western North America. 

It’s also been connected to a phenomenon California meteorologists dubbed the <a href="https://weatherwest.com/archives/tag/ridiculously-resilient-ridge">Ridiculously Resilient Ridge</a>, believed to have played a large role in the <a href="https://www.earth.com/news/california-drought-changing-landscape/">drought that plagued the state</a> from 2011 to 2016.

Now, Alaska and northwestern Canada are seeing the “son of the Pacific blob,” Armel Castellan of <a href="https://www.canada.ca/en/environment-climate-change.html">Environment and Climate Change Canada</a> said. 

"To see a blob sort of establish itself at this time of year is sort of surprising," Castellan told <a href="https://www.cbc.ca/news">CBC News</a>. "It's a symptom of the enduring or stagnant weather we've been having over the last four years."

Alaska is already seeing unseasonably warm temperatures, and northern British Columbia is still experiencing summer-like weather. Alaska just ended one of its warmest Septembers in 94 years, according to the <a href="https://www.climate.gov/news-features/event-tracker/alaska's-2018-early-fall-extremes">National Oceanic and Atmospheric Administration</a>. Parts of southern Italy are experiencing a drought.

The Pacific blob of warm water creates a high-pressure period, which changes the direction of the Pacific Jet Stream. That causes warmer weather, and in the case of California’s Ridiculously Resilient Ridge, prevented normal winter storms from making landfall where they’re most needed.

Right now, if the Pacific blob fails to dissipate, Alaska, the Pacific Northwest, Montana, northern Wyoming and western North Dakota could see warmer-than-usual temperatures into the winter. 

A side effect of the Pacific blob seems to be colder and wetter than usual weather in the U.S. Southeast and the Mid-Atlantic states.

Phenomena like the Pacific blob are becoming more common, meteorologists say.

"It's definitely something we're starting to see with these resilient ridges," Castellan said. "It just begs the question of how much of this is linked to climate change."

—

Image credit: Rick Thoman, based on OISST data from <a href="https://www.esrl.noaa.gov/">NOAA Earth System Research Lab</a>.

Pacific blob returns, bringing warm days and fear of drought

The Pacific blob is back, and that could spell bad...

How can we know how long we’re going to <a href="http://www.earth.com/news/life-expectancy-2040/">live</a>? The true answer is that we can’t, but new research from the <a href="https://www.ed.ac.uk/">University of Edinburgh</a> may help give some people a better idea of their projected lifespan.

In recent research presented at the <a href="http://www.ashg.org/">American Society of Human Genetics</a> annual meeting, scientists detail how they devised a way to estimate whether an individual can expect to live longer or shorter on average. Their approach came from studying the effect of genetic variations on lifespan across the human genome.

Through the largest ever genome-wide association study of lifespan, the researchers combined genetic data from more than 500,000 participants in the UK Biobank and other cohorts with data on the lifespan of participant’s parents. The effects of just a single gene on lifespan are tiny, so this larger sample size was needed to identify the genes relevant to our lifespan. This sample helped researchers validate six previously identified associations between specific genes and aging – such as the APOE gene, which has been linked to risk of neurodegenerative disease. 

Additionally, the research team found 21 new genomic regions that have an influence on the human lifespan. They then used their results to create a polygenic risk score for lifespan, which is a personalized genomic score that estimates an individual’s genetic likelihood of a longer life.

“Using a person’s genetic information alone, we can identify the 10 percent of people with the most protective genes, who will live an average of five years longer than the least protected 10 percent,” explains Paul Timmers, a graduate student at the University of Edinburgh.

The study also dove deeper into the specifics of the effects of genetic variants on the aging process, as the researchers wanted to determine whether certain variants were affecting aging directly or influencing the risk of individual diseases that could lead to death. They discovered that among common variants, the genes associated with Alzheimer’s disease, heart disease, and smoking-related conditions were linked to overall lifespan. Interestingly, they did not find lifespan associations for other cancers, which may suggest that the risk of death due to other cancers is a result of rarer genetic variants or the environment.

“This was an interesting result,” says Timmers. “We suspect that the variants we found, such as for smoking and Alzheimer’s disease, pertain uniquely to the modern period of human history. For example, a genetic propensity to smoke wasn’t harmful before we discovered tobacco, but it is now. Since natural selection has not yet had many generations to act on these variants, the variants are still fairly common.”

Moving forward, the researchers plan to study how the variants and functional pathways they identified affect lifespan.

--

By <a href="mailto:certz@earth.com">Connor Ertz</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

New lifespan “score” can help predict how long you might live

How can we know how long we’re going to live?...

The oldest known fossils on Earth may actually be nothing more than just some regular rocks, according to a new study by <a href="https://www.nasa.gov/">NASA</a> astrobiologist Abigail Allwood. 

The structures, which were discovered by a team of Australian scientists in Greenland two years ago, were thought to date back 3.7 billion years. The results of that study suggested that scientists had underestimated how quickly and easily life on Earth had formed.

In the current investigation, however, advanced NASA technology used by Allwood indicated that the material found in Greenland is more rock than <a href="http://www.earth.com/news/fossils-modern-birds-dinosaurs/">fossil</a>.

[caption id="attachment_1861096" align="aligncenter" width="700"]<a href="https://www.earth.com/wp-content/uploads/2018/10/Are-the-“oldest-fossils-on-Earth”-really-just-average-rocks.png"><img class="wp-image-1861096" src="https://www.earth.com/wp-content/uploads/2018/10/Are-the-“oldest-fossils-on-Earth”-really-just-average-rocks.png" alt="" width="700" height="332" /></a> Image Credit: Allen Nutman[/caption]

Allwood was responsible for finding the previously oldest fossil, which is nearly 3.5 billion years old. After the 2016 study emerged, she went to Greenland to investigate.

Allwood determined that the shapes, weathering and the interior layers of the structures did not fit the characteristics of ancient fossils, known as stromatolites. She mapped the composition of the fossils in question, and concluded that they do not have the chemical signature of fossilized life.

According to the <a href="https://www.ap.org/en-us/">Associated Press</a>, several experts agree with Allwood that the fossils were dated incorrectly by Allen Nutman and colleagues at the University of Wollongong in Australia.

Despite the new findings, the Australian scientists maintain that the odd structures are partially made up of material from microbes that lived on an ancient seafloor. They argue that Allwood took samples from the far end of one of two sites and did not test the original specimens that were offered for analysis.

“This is a classic comparing apples and oranges scenario, leading to the inevitable outcome that ours and their observations do not exactly match,” the Australian researchers said in a statement.

The study is published in the journal <a href="http://www.nature.com/">Nature</a>.

--

By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Are the “oldest fossils on Earth” really just average rocks?

The oldest known fossils on Earth may actually be nothing...

Cancer is a ticking time bomb in our bodies. If there were an equation for cancer it would mainly consist of mutations + time = cancer. And it’s no secret that if we live long enough, we’ll likely experience some form of <a href="http://www.earth.com/news/air-pollution-mouth-cancer/">cancer</a> ourselves. 

A recent study published in the journal <a href="https://www.sciencemag.org/">Science</a> has found that by the time we reach middle age, over half the esophagus in healthy people has been taken over by cells containing mutations in cancer genes. The report details how mutant cells mutate and compete with each other over time – with only the fittest mutations surviving.

Scientists at the Wellcome Sanger Institute, MRC Cancer Unit, <a href="https://www.cam.ac.uk/">University of Cambridge</a> along with collaborators have uncovered for the first time evidence that healthy cells in the esophagus carry at least several hundred mutations per cell on average in people in their twenties. These mutations only increase as we age, and rise to over 2,000 mutations per cell later in life. 

However, it’s important to note that only mutations in a dozen or so genes really matter when it comes to cancer, as these mutations give the cells a competitive advantage and allow them to take over the tissue, forming a dense patchwork of mutations.

The researchers made this discovery through studying normal esophageal tissue. 

“Under the microscope, the esophageal tissue looked completely normal – it came from healthy individuals who had no signs of cancer,” explains lead author Phil Jones, a professor at the University of Cambridge. “After studying the genetics we were shocked to see that the healthy esophagus was riddled with mutations. We discovered that by the time an individual reaches middle age, they probably have more mutant than normal cells.”

Using targeted and whole-genome sequencing to map groups of mutant cells in esophageal tissue, scientists found that these mutations ran rampant even in individuals with no history of esophageal cancer or any related problems.

Additionally, this research has brought new understanding to the mutations that are found in the squamous form of esophageal cancers. Mutations in the NOTCH1 gene – known to control cell division – were found in almost half of all cells in the normal esophagus by middle age. But a mutated gene known to be found in almost all esophageal cancers – TP53 – was only found to be mutated in 5 to 10 percent of normal cells. These findings suggest that researchers may need to reevaluate the role of some genes believed to be responsible for cancer, as it’s possible that the NOTCH1 mutation could possibly protect cells against cancer development, rather than being responsible for it.

“We have found that genetic mutations associated with cancer are widespread in normal tissues, revealing how our own cells mutate, compete and evolve to colonize our tissues as we age,” says Dr. Inigo Martincorena, joint lead author from the <a href="https://www.sanger.ac.uk/">Wellcome Sanger Institute</a>. “Given the importance of these mutations to cancer, it is remarkable that we have been unaware of the extent of this phenomenon until now. While the work sheds light on early cancer development, it also raises many questions about how these mutations may contribute to ageing and other diseases, opening interesting avenues for future research.”

--

By <a href="mailto:certz@earth.com">Connor Ertz</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Average healthy esophagus still accumulates hundreds of mutations

Cancer is a ticking time bomb in our bodies. If...

The holidays are coming up, and it’s more likely than not that you’ll soon be standing over a table full of <a href="http://www.earth.com/news/fast-food-restaurants-unhealthy-options/">food</a>, brain firing with anticipation and building the perfect plate in your mind before you dig in. In these situations, we have to make quick decisions about which dishes to try and how much of each to take. While you may think these decisions are made mainly by your stomach, neuroscientists at <a href="https://www.jhu.edu/">Johns Hopkins University</a> have now found the region of your brain that is strongly linked to food preference decisions.

The research team wanted to find out how the brain determines what to eat and how much of it to eat when an individual has several good food options. Even if there are similar foods available that we desire somewhat equally, the favorite dish will likely be eaten faster and with bigger bites.

In their study, the scientists gave rats two similar sugary drinks. The rats preferred the drink made with sucrose over the one made with maltodextrin – so that when they receive sucrose, they’d lick it up faster. Over the course of multiple days, the rats were given either one drink or the other while the researchers mapped their brain activity at the exact moment the animals realized which drink they received. Thus, the neuroscientists could pinpoint the neurons that registered excitement for sucrose, and the disappointment for maltodextrin.

“We found a region in the brain that reflects our perception of food in a strikingly dominant way,” says lead author David Ottenheimer, a Johns Hopkins University graduate student studying neuroscience. “The level of brain activity we saw exceeded our expectations by far.” The neurons that were activated are in a region called the ventral pallidum, an area that has long been associated with reward and pleasure perception – but always considered to be in more of a secondary role.

The researchers then presented the rats with a different set of options – either the maltodextrin drink or plain water. They found that when the rats got maltodextrin, these neurons fired like they had for sucrose. These results indicate that the brain area is making context-dependent decisions, responding to the best food option at any given time.

“Because the signaling by ventral pallidum neurons changes immediately when the rat changes his ranking of which flavor is his favorite, we see this response as providing a real-time readout of what you like best from currently available options,” says senior author <a href="https://pbs.jhu.edu/directory/patricia-janak/">Patricia Janak</a>, a Bloomberg Distinguished Professor of Psychological and Brain Sciences and Neuroscience.

Although more research is needed to figure out what the signaling in this region of the brain really means, the team believes their study could be key to developing therapies and treatments that encourage healthy eating. “Our data suggest that further investigation of ventral pallidum will be critical for understanding how we make decisions about eating,” says Ottenheimer. “If we want to figure out why a food can be exciting in one scenario and disappointing in another, ventral pallidum could be the key.”

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By <a href="mailto:certz@earth.com">Connor Ertz</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

What determines our food preferences and decisions?

The holidays are coming up, and it’s more likely than...

A new study has found that the herpes virus has been linked to Alzheimer’s disease, and that people with severe herpes benefit from taking antiviral drugs as they decrease the risk of developing dementia. 

A new paper by Ruth Itzhaki, a professor at the <a href="http://www.manchester.ac.uk/">University of Manchester</a>, was published in the journal <a href="https://www.frontiersin.org/articles/10.3389/fnagi.2018.00324/ful">Frontiers in Aging Neuroscience </a>and reviews 25 years of research examining the link between herpes and <a href="http://www.earth.com/news/exercise-benefits-alzheimers/">Alzheimer’s</a>. 

Itzhaki is a leading expert on Alzheimer’s and it’s connection to HSV1, the Herpes Simplex Virus 1. 

Herpes viruses remain in a person’s immune cells, and neurons for the entirety of their life and flare-ups or reactivation of the virus can happen when stress or illness puts a strain on the body’s immune system. 

It’s been theorized and extensively studied that because HSV1 infects neurons, during reactivation, the infected neurons cause mental deterioration. 

“Viral DNA is located very specifically within plaques in postmortem brain tissue from Alzheimer's sufferers,” said Itzhaki. “The main proteins of both plaques and tangles accumulate also in HSV1-infected cell cultures - and antiviral drugs can prevent this.”

Carriers of the gene variant APOE-ε4 are particularly at risk of developing Alzheimer's later on in life. 

“HSV1 could account for 50% or more of Alzheimer's disease cases,” said Itzhaki, “Our theory is that in APOE-ε4 carriers, reactivation is more frequent or more harmful in HSV1-infected brain cells, which as a result accumulate damage that culminates in development of Alzheimer's.” 

To prove this, Itzhaki analyzed data from <a href="https://nhird.nhri.org.tw/en/">Taiwan’s National Health Insurance Research Database</a>. 

The database is appealing to researchers like Itzhaki because 99.9 percent of Taiwan’s population is enrolled in it and there is a lot to be learned about microbial infections and diseases from such a large sample. 

Three studies were published in 2017 and 2018 using the National Health Insurance Research Database to investigate the development of senile dementia and the success of treatments administered to patients with obvious signs of HSV1 infection. 

“The striking results include evidence that the risk of senile dementia is much greater in those who are infected with HSV, and that anti-herpes antiviral treatment causes a dramatic decrease in number of those subjects severely affected by HSV1 who later develop dementia,” said Itzhaki.

Itzhaki notes that the results only apply to patients with severe HSV1 infections but that over 150 publications provide evidence to support the theory that HSV1 influences Alzheimer's. 

--

By <a href="mailto:kayvandette@gmail.com">Kay Vandette</a>, <a href="https://www.earth.com/">Earth.com</a> Staff Writer

New study shows that herpes can increase risk of Alzheimer’s

A new study has found that the herpes virus has...

Kisspeptin, a hormone responsible for regulating reproduction, has a much stronger influence on regulating mood and brain activity than previously realized. 

Researchers from <a href="https://www.imperial.ac.uk/">Imperial College London</a> studied kisspeptin and its effect on brain activity during the brain’s resting state, something that had never been done before. 

“Although we have previously investigated how this hormone affects the brain when it is in an active state, this is the first time we've demonstrated it also affects the brain in its baseline, resting state,” said Waljit Dhillo, the senior author of the study. “These insights suggest the hormone could one day be used to treat conditions such as low sex drive or depression.” 

Think of the resting state like a car in neutral. It’s a period when the brain isn’t concentrating on a task, and studies that delve into the brain’s resting state are providing new insights into the active <a href="http://www.earth.com/news/switch-turns-brain-off-sleep/">brain</a> and psychological disorders. 

Kisspeptins were discovered along with the gene that produces them, KISS1, in 1996. KISS1 and kisspeptin are named after <a href="https://www.thelancet.com/pdfs/journals/landia/PIIS2213-8587(13)70098-6.pdf">Hershey’s Kisses</a> because the gene was discovered in Hershey, Pennsylvania. 

Studies have shown that kisspeptin <a href="https://www.physiology.org/doi/full/10.1152/physiol.00009.2010">is a “master regulator” of reproduction</a> and the researchers wanted to better understand how the hormone influences brain activity. 

According to the researchers, the study could help pave the way for new treatments for problems like low sex drive. 

For the study, 29 men were given a kisspeptin infusion and shown an array of themed images while they were in an MRI scanner. The images were either sexual, negative, or neutral in nature and the researchers monitored brain activity as the participants viewed the images. 

In a second visit, the participants were given a placebo and asked to take part in the same MRI test, but the men didn’t know that they had not been given the hormone. 

The results were published in the Journal of Clinical Investigation Insight, and the researchers found links between the hormone and decreased sexual aversion and increased sexual arousal during resting states. 

“Our findings help unravel the many and complex roles of the naturally-occurring hormone kisspeptin, and how it orchestrates reproductive hormones as well as sexual and emotional function,” said Alexander Comninos, the first author of the study. “Psychosexual problems, such as low sex drive, affect up to one in three people, and can have a devastating effect on a person's, and a couple's, wellbeing. These findings open avenues for kisspeptin as a future treatment for these problems, although there is a lot of work still to be done.”

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By <a href="mailto:kayvandette@gmail.com">Kay Vandette</a>, <a href="https://www.earth.com/">Earth.com</a> Staff Writer

Image Credit: Imperial College London

Hormone that regulates reproduction could treat low sex drive

Kisspeptin, a hormone responsible for regulating reproduction, has a much...

For many decades, scientists have explored the theory of panspermia, the idea that life itself can be transferred through <a href="http://www.earth.com/news/life-recovered-asteroid-dinosaurs/">asteroids</a> and other space objects. Panspermia depends upon whether the microorganisms and chemicals that are necessary for life could survive being transported from one stellar system to another.

Researchers at the <a href="https://www.cfa.harvard.edu/">Harvard Smithsonian Center for Astrophysics</a> (CfA) have recently investigated the possibility of panspermia on a galactic scale. The study revealed that “the entire Milky Way could potentially be exchanging biotic components across vast distances.”

Study lead author Idan Ginsburg told <a href="https://www.universetoday.com/">Universe Today</a>: “We expect most objects to likely be rocky, but in principle they could also be icy (cometary) in nature.”

“Regardless of whether they are rocky or icy, they can be ejected from their host system and travel potentially thousands of light-years away. In particular the center of the galaxy can act as a powerful engine to seed the Milky Way.”

The team constructed a model to estimate how many icy or rocky bodies may reach a new star system, as well as the likelihood that any life contained on them would survive.

“We estimate the capture rate of objects ejected from planetary systems over the entire phase space as well as time,” wrote the study authors. “We further take into account the number of stars that an interstellar object traverses, as well as the scale height and length of the Milky Way's disk.”

The results of the study suggest that life could, in fact, be spread throughout the galaxy that contains our solar system.

“It’s like billiards,” said Ginsburg. “You hit the cue ball and it hits the other balls, and beside just transferring momentum it also spreads life, and then life spreads across the whole table, which is the galaxy.”

The researchers concluded that up to 100 million life-bearing objects with a radius of 200 kilometers could have been captured by planetary systems around the Milky Way. While smaller objects are more likely to survive the journey, microbial content would have less shelter and would be more exposed to the harsh conditions of outer space.

“It’s a very dangerous ride, but you can think of the microbes as tiny astronauts sitting in a natural spacecraft,” said study co-author Abraham Loeb. “I would actually be thrilled to be a microbe sitting in a rock that makes it across the Milky Way.”

After a space body is captured into a new orbit, it would have to smash into a planet to transfer any life that it may be carrying. In the past, many rocks from Mars crashed into the Earth, which has caused some scientists to speculate that life on our planet originated on Mars. According to Loeb, it is even possible, if unlikely, that life on Earth began with interstellar microbes.

The study is being reviewed for publication by the <a href="https://academic.oup.com/mnras">Monthly Notices of the Royal Astronomical Society</a>.

--

By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Space rocks could be carrying life across the milky way

For many decades, scientists have explored the theory of panspermia,...

Scientists are transforming chocolate into a functional food by infusing it with probiotics and prebiotics, aiming to create a treat that satisfies cravings while supporting gut health. 



The challenge lies in maintaining chocolate's beloved texture and flavor while adding health benefits.



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Probiotics - beneficial microbes that balance gut bacteria and aid digestion - are typically fragile and can be destroyed by stomach acid or processing. 



Prebiotics act as food for these microbes, helping them thrive. Together, they form "synbiotics," a powerful health combination.



Researchers Smriti Gaur and Shubhi Singh from India's Jaypee Institute of Information Technology took an innovative approach, using natural prebiotics like corn and honey instead of complex processing methods. 



They created five chocolate varieties: a control and four synbiotic versions containing different combinations of prebiotics, probiotics (Lactobacillus strains), and flavor enhancers (cinnamon or orange).



Laboratory simulations of human digestion showed the probiotics remained viable for over five hours, suggesting they could survive long enough to benefit gut health.



Taste tests were positive, with researchers particularly enjoying the orange-flavored variety, describing it as having "vibrant citrus notes" complementing the "rich cocoa" with a "luxurious" texture.



This research represents just the beginning. With further refinement of strains, textures, and flavors, chocolate could evolve beyond mere indulgence to become a functional food that nourishes while it delights.



The study is published in the journal <a href="https://pubs.acs.org/doi/10.1021/acsfoodscitech.4c00741" target="_blank" rel="noreferrer noopener">ACS Food Science &amp; Technology</a>.

Is chocolate the next nutritional powerhouse?

Scientists are transforming chocolate into a functional food by infusing...

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Nushagak Bay, a large estuary in southwest Alaska. Nushagak runs mainly north to south and exits in Bristol Bay, a large body of water in the Bering Sea.



"The bay is primarily fed by the Nushagak River, which begins in the Alaska Range and flows southwest approximately 450 km. The bay is also fed by several additional rivers including the Wood, Igushik, Snake and Weary rivers," says ESA.



"The dark colors of the Nushagak River are most likely due to tannins or lignins (chemical substances found in plants). Tannins and lignins from roots, leaves, seeds, bark and soil can leach into the water and give it a brown or even black colour. The sediments then flow southwards where it is mixed with the bluer waters of the bay."



Video/ Image Credit: ESA



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Nushagak Bay in southwest Alaska

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Today's Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> (ACS) reveals that proteins on flu viruses are actually flexible, tilting and waving in a “breath-like” motion. According to the experts, these proteins could be used to better defend against the flu.



"The main antigenic targets of influenza virus are two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Whereas the structural and dynamical properties of both glycoproteins have been studied previously, the understanding of their plasticity in the whole-virion context is fragmented," wrote the researchers.



To investigate, the team conducted detailed simulations of the influenza A H1N1 virion, or the swine flu. The experts concluded that the visualizations show many new vulnerable states of flu viruses, which could improve future vaccines and antiviral drugs.



Video/ Image Credit: American Chemical Society&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Flu viruses are more flexible than expected

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Lake Trasimeno, which is located west of Perugia in central Italy. It is the fourth largest lake in the country. While Trasimeno’s water level varies, it has a maximum depth of approximately six meters.&nbsp;



"In this Copernicus Sentinel-2 image, captured on 6 August 2022, the lake’s emerald green colour is likely due to the presence of phytoplankton. Streaks in the water, particularly visible in the west, indicate the presence of soil and sediments which have been stirred up by winds. Dark colored waters in the southern part of the lake indicate a presence of submerged and floating macrophytes (aquatic plants) as well as algae," says ESA.



"Surrounded by hills on three sides, Trasimeno is subject to heavy storms created by winds, especially from the north and west. There are three islets in the lake: Maggiore, Minore and Polvese (the largest). The lake’s shores are sparsely inhabited with only two popular villages: Castiglione del Lago and Passignano sul Trasimeno."



"Italy is experiencing its worst drought in 70 years which has affected drinking water supplies, hydroelectric power and agricultural production. High temperatures, hot winds and lack of rainfall are the main causes of drought in the Umbrian region which saw Lake Trasimeno’s drop 1.3 m, reaching the limit of the hydrometric zero in July 2022."



Video/Image Credit: ESA&nbsp;



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Lake Trasimeno in Central Italy

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Today's Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> describes a new self-powered nanosensor that can instantly detect mercury contamination with the tap of a finger.&nbsp;



The oxidized form of mercury can be harmful when it is ingested through contaminated water or food. This makes it necessary for experts to develop sensors that can quickly and accurately detect the presence of mercury.&nbsp;



Zong-Hong Lin and colleagues have now created a triboelectric nanosensor (TENS) that can detect mercury by simply by touching a sample. According to the researchers, their TENS could serve as the basis for similar devices to safely and remotely monitor other pollutants.



Video Credit: American Chemical Society&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Detecting mercury contamination with the tap of a finger

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Kainji Lake, a reservoir on the Niger River.



In 1968, Kainji Lake was created by the construction of the Kainji Dam. The Niger River, the third longest in Africa, enters the lake in the north.&nbsp;



According to <a href="https://www.earth.com/news/rivers-in-the-american-west-are-a-lifesaving-resource-for-birds/">ESA</a>, the creation of the lake submerged Foge Island and the town of Bussa and permanently flooded other riverine settlements, leaving around 50,000 people displaced.&nbsp;



Large parts of Foge Island are temporarily exposed during low water tides, and the land is often used by migrating fishermen. Kainji Dam is a dam across the Niger River in Niger State of Central Nigeria. 



Wild mammals occur at relatively low densities due to illegal hunting. Lake Kainji has suffered a dramatic decline as a fishery due to the high numbers of artisanal and subsistence fisherfolk using the lake. It has been suggested that a period of closure, together with controlled fishing rights may help improve fish stocks.



Kainji Lake National Park is the oldest of its kind in Nigeria. The park contains three distinct areas: a part of the Kainji Lake, the Borgu Game Reserve to the west of the lake, and the Zugurma Game Reserve to the southeast. The park is home to around 65 mammal species, 350 bird species, and 30 species of reptiles and amphibians. 



Video/ Image Credit: European Space Agency&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Kainji Lake in north central Nigeria

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Today’s Video of the Day from <a href="https://www.igb.illinois.edu/">Carl R. Woese Institute for Genomic Biology</a> reveals how scientists can modify common crops like soybean, rice, and wheat to protect them from heat stress.



“We need to double crop production by 2050 to feed a growing global population, and not only are we not on track to do that, but climate change is further complicating things,” said Amanda Cavanagh, a lecturer at the University of Essex. 



The study is part of Realizing Increased Photosynthetic Efficiency (RIPE), an international research project that aims to develop food crops that turn the sun’s energy into food more efficiently.



“Using an engineering approach we designed multiple alternative metabolic pathways to photorespiration. Testing them in the field showed increases in productivity which led Amanda to significantly move the project forward by showing our engineered plants can withstand pretty extreme temperature stress,” said study co-author and RIPE researcher Paul South.&nbsp;



“As the climate changes and temperature stresses increase the pressure on our global food supply, farmers will need every tool available including engineering approaches like the synthetic biology used here to maintain safe and productive harvests.”



The experts tested plants modified to have more efficient photorespiration to see if they were better adapted to warmer temperatures.&nbsp;



The team found that the engineered plants produced 26 percent more biomass than the wild-type plants exposed to the same temperatures, and had 15 percent less yield loss under the higher temperatures.



Video Credit: Amanda Nguyen/University of Illinois



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Designing crops that can beat the heat

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Today’s Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> explores the ability of salt to transform the way that foods and beverages taste. Salt is known to cover up undesirable flavors, such as bitterness in coffee or beer, but how exactly does sodium chloride change the taste of other compounds?



One previous study showed that, not only does salt suppress bitterness, but also enhances sweetness and sourness. Another study revealed that bitterness reduction by salt seems to be happening at the tongue receptor level as well as in the brain.&nbsp;



While it is known that salt taste is mediated by the presence of sodium channels in the form of taste buds, experts believe that there is also an unknown receptor responsible for how we taste salt that has not yet been identified.&nbsp;



Video Credit: ACS Reactions



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

How does salt makes things taste better?

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Santiago, the capital city of Chile. The city is located in the center of the Santiago Metropolitan Region, which has a population of about eight million people.&nbsp;



'The weather of Santiago resembles the Mediterranean climate with dry and warm summers with temperatures reaching up to 35°C (from October to March) and cool and humid winters that can drop to 0°C (from April to September)."



"The city lies in the centre of the country’s central valley around 80 km from the Pacific Ocean to the west and borders Argentina to the east. A tiny part of Argentina is visible in the top-right corner of the image where the mountain crest of the Andes Mountains acts as a divider between the two countries," says ESA.



Video/ Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Santiago, Chile in South America

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Astronomers at <a href="https://www.jhu.edu/">Johns Hopkins University</a> have created an interactive map of the universe, including the actual position and real colors of 200,000 galaxies. The map allows the public to access data that was previously only available to scientists.



The map was developed using data collected by the Sloan Digital Sky Survey. For over two decades, a telescope in New Mexico was aimed at slightly different locations to capture the night sky.&nbsp;



"Growing up I was very inspired by astronomy pictures, stars, nebulae and galaxies, and now it's our time to create a new type of picture to inspire people," said map creator Brice Ménard, a professor at Johns Hopkins. "Astrophysicists around the world have been analyzing this data for years, leading to thousands of scientific papers and discoveries. But nobody took the time to create a map that is beautiful, scientifically accurate, and accessible to people who are not scientists. Our goal here is to show everybody what the universe really looks like."



"In this map, we are just a speck at the very bottom, just one pixel. And when I say we, I mean our galaxy, the Milky Way which has billions of stars and planets. We are used to seeing astronomical pictures showing one galaxy here, one galaxy there or perhaps a group of galaxies. But what this map shows is a very, very different scale."



"From this speck at the bottom, we are able to map out galaxies across the entire universe, and that says something about the power of science."



The <a href="https://mapoftheuniverse.net/">interactive map</a> is available online, where it can be downloaded for free.



Video Credit: Johns Hopkins&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Interactive map of the universe includes 200,000 galaxies

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Today's Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes the first comprehensive estimate of carbon density in the Saharan, Sahel, and Sudanian zones of Africa. In an effort to measure the amount of carbon stored across these drylands, a team of scientists used high-resolution satellite images and artificial intelligence to map nearly 10 billion individual trees. 



"The high spatial resolution (50 cm) combined with AI and field measurements used in this study is key to improving tree inventories in drylands," said Pierre Hiernaux, a French researcher working for NASA. "The ever-increasing availability of very high-resolution satellite imagery will make it possible to assess carbon pools and their dynamics at the individual tree level on a global scale."



"This study is exceptional because it is pioneering a type of approach that will revolutionize the monitoring of trees and forests on a global scale: in the short term, it will be possible to map the world's trees from the centre of the Amazon to our schoolyards," said <a href="https://www.inrae.fr/en">INRAE</a> researcher Jean-Pierre Wigneron.



"Many fields of application will become much more efficient and accurate, such as tracking carbon stocks, biodiversity, monitoring logging and protection against illegal forest degradation, in near real time.”



Video Credit: NASA Goddard&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Remote sensing will revolutionize the way we monitor trees

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Today's Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Dublin, the capital and largest city of Ireland. Beyond its pub culture, Dublin is known as a modern culinary destination and a UNESCO City of Literature.



"Dublin is located near the midpoint of Ireland’s east coast in the province of Leinster. The city, which covers an area of around 115 square kilometers, is bordered by the Dublin Mountains, a low mountain range to the south, and is surrounded by flat farmland to the north and west," says ESA.



"The city straddles the River Liffey, which rises in the Wicklow Mountains and flows around 80 kilometers eastwards through the city of Dublin, in which it is canalised and bordered with quays. It then empties into Dublin Bay, an arm of the Irish Sea."



Dublin has an abundance of green spaces, including one of the largest enclosed public parks in any European capital city. Phoenix Park, which was originally formed as a royal hunting park in the 1660s, includes 707 hectares of green space.



Video Credit: ESA&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

The city of Dublin on Ireland's east coast

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Today's Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features the province of Zaragoza in northeast Spain. The image was captured by the Copernicus Sentinel-2 mission.



"Together with the provinces of Huesca and Teruel, Zaragoza formed the old kingdom of Aragon. Its capital, also called Zaragoza (not visible in this image) is home to around half of Aragon’s population," says ESA.



"The Ebro River can be seen winding its way through the province from west to east in this image. Between its source in the Cantabrian Mountains in the northwest and its delta on the Mediterranean coast, the Ebro River is fed by more than 200 tributaries as it flows 910 km across much of northern Spain."



Since rainfall is very scarce in this region, irrigation in the Ebro basin is critically important. In the valleys surrounding the Ebro River, many fields are used for growing crops such as corn, wheat, and barley.



Video/ Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

The province of Zaragoza in northeast Spain

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Today's Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> features a visual dataset of.methane emissions from wetlands across the globe. Atmospheric methane levels have reached record highs in recent years, and wetlands are a major source of these emissions.&nbsp;



"Methane is an important greenhouse gas that contributes substantially to global warming. On a molecule by molecule basis, methane is much more efficient at trapping heat than carbon dioxide, the main driver of warming," says NASA.



"Though human activities, including agriculture, oil and natural gas production and use, and waste disposal, collectively contribute the majority of methane to the atmosphere, about a third of total methane emissions comes from wetlands."&nbsp;



According to NASA, understanding methane emissions from wetlands and other natural sources is critically important for scientists and policymakers who are working to combat climate change by reducing emissions from human activities.



Video Credit: NASA Goddard



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Wetlands are a major source of methane emissions

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Today’s Video of the Day from <a href="https://earthobservatory.nasa.gov/">NASA Earth Observatory</a> reveals the evolution of the Columbia Glacier in southeastern Alaska. Columbia is among the fastest shrinking glaciers in the world, and the video documents its rapid retreat over the years.&nbsp;



Columbia Glacier is a large, multi-branched calving glacier that flows out of the Chugach Mountains to the Prince William Sound.&nbsp;



According to USGS, Columbia had a long history of stability prior to 1980, with a length 41 miles, and small, short-lived advances or retreats.



In the years since 1980, however, satellite images have captured Columbia’s alarming retreat. By using false-color images, scientists can distinguish between snow and ice, open water, vegetation, and rocky debris on the glacier’s surface.



The series of false-color images featured in today's video were acquired over the span of 35 years. You can see that by 2021, the glacier’s main branch had retreated about 15 miles from its initial position.



The Columbia Glacier has also lost more than 50 percent of its volume, mostly due to calving. <a href="https://www.earth.com/video/nasa-reveals-3d-visual-of-an-atmospheric-river/">NASA</a> reports that while climate change likely started the retreat, mechanical processes kept the disintegration going.



The NASA images are provided by Jesse Allen, Robert Simmon, Joshua Stevens, and Lauren Dauphin using data from Landsat satellites, from the U.S. Geological Survey, and data from MODIS on NASA’s Terra satellite. The structure of Columbia’s moraine played a large role in the stability of the glacier before 1980. 



Like other tidewater glaciers, the Columbia built up a moraine over time, and the mixture of ice and rock functioned like a dam keeping out the sea. It was supported on one end by the shoreline and by the underwater terminal moraine at the other.



Video Credit: NASA Earth Observatory/&nbsp; NASA’s Scientific Visualization Studio



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

The rapid retreat of the Columbia Glacier

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features the Pyrenees Mountains, which form a natural boundary between France and Spain in southwest Europe.



The mountain range is 430 kilometers in length. It stretches from the Mediterranean Sea on the east to the Atlantic Ocean on the west.



At an elevation of 3404 meters, Pico de Aneto is the highest mountain peak in the Pyrenees, and the third-highest peak in Spain. Pico de Aneto is located in the Posets-Maladeta Natural Park, which spans more than 82,000 acres.&nbsp;



"Geological studies have revealed that the Pyrenees Mountains have been around for longer than the Alps, with their sediments first deposited in coastal basins during the Paleozoic and Mesozoic eras," reports ESA.



"The entire mountain range formed due to the upwelling of large sedimentary rocks by the collision of the Iberian and the Eurasian plate around 100 to 150 million years ago, followed by intense erosion from ice and water."



The western Pyrenees receive more precipitation due to moisture blowing in from the Atlantic Ocean. The mountain range contains many lakes, several small glaciers, and some of the highest waterfalls in Europe.



Video &amp; Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

The Pyrenees Mountains in southwest Europe

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Today’s Video of the Day from <a href="https://www.stowers.org/">Stowers Institute for Medical Research</a> describes why experts are studying zebrafish to gain a better understanding of how the immune system responds to injury. Zebrafish have the ability to repair and regenerate organs.



“Organ regeneration offers an exciting opportunity for studying the immune system and to inquire why some species can regenerate organs like the heart or missing limbs while others like humans cannot,” explained Dr. Tatjana Piotrowski.



Zebrafish sensory organ hair cells are an ideal system to investigate the pathways and cell types involved in regeneration since they are easily destroyed with antibiotics and begin regenerating within five hours. This enabled the researchers to identify the exact timing and genetic programs for each anti-inflammatory macrophage activation state.&nbsp;



“Our hypothesis is that human macrophages do not receive the proper chemical activation 'cocktail' to instruct pro-regenerative processes,” said Dr. Nicolas Denans. “Identifying the molecular recipe of macrophage activation in zebrafish may one day enable us to design regenerative immunotherapies in humans.”&nbsp;&nbsp;&nbsp;



“The new evidence is a valuable resource for comparative studies on the genetic programs involved in macrophage-mediated repair and regeneration. In other words, different types of injuries may induce different kinds of inflammatory responses. We want to decipher whether this 'language' is universal or if there are a variety of dialects."



Video Credit: Stowers Institute for Medical Research&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

How the immune system responds to injury

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Today's Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes how record-breaking heat expressed itself around the world in 2022.



Scientists have determined that 2022 was the 5th warmest year since 1880. Furthermore, the last nine consecutive years have been the warmest on record.



From devastating floods and wildfires to natural disasters like Hurricane Ian, 2022 showed us yet again how a warming climate affects people across the globe.&nbsp;



"As we look back at 20:22 and years past, we see that each year we better understand the challenges we face and how important it is to meet them," says NASA.



Video/ Image Credit: NASA Goddard



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

2022 illustrated the consequences of a warming climate

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Today's Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes two exoplanets that are orbiting a star 218 light-years away. A team of researchers led by the University of Montreal has found evidence that these planets are "water worlds."



The experts used data from NASA’s Hubble and Spitzer Space Telescopes. They discovered that exoplanets Kepler-138 c and Kepler-138 could be composed largely of water.



"We previously thought that planets that were a bit larger than Earth were big balls of metal and rock, like scaled-up versions of Earth, and that's why we called them super-Earths," explained study co-author Björn Benneke.&nbsp;



"However, we have now shown that these two planets, Kepler-138 c and d, are quite different in nature and that a big fraction of their entire volume is likely composed of water. It is the best evidence yet for water worlds, a type of planet that was theorized by astronomers to exist for a long time."



Video Credit: NASA Goddard



Image Credit: NASA, ESA, and Leah Hustak (STScI)



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Two distant planets may be "water worlds"

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Satellites reveal how Earth's systems are interconnected Today’s Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes Earth’s interconnected systems, and how this network is affected by rising temperatures.&nbsp;



During 2020, average global temperatures matched the hottest year on record. The hurricane season was also record-breaking, with many of the storms intensifying at extraordinary speeds. Hot water in the ocean is fuel for hurricanes. The satellite data shows that it's all one interconnected system showing how Satellites reveal how Earth's systems are interconnected.



According to NASA, dust swept up from Northern Africa plays a major role in the formation of hurricanes, and is also a key source of fertilization in the Amazon rainforest. As a result of<a href="https://www.earth.com/news/seagrass-wasting-disease-is-fueled-by-climate-change/"> climate</a> change, dust plumes are expected to decline, which will have an effect on vegetation far away.&nbsp;



Images from Earth-observing satellites show how the world’s plant life is affected by natural disasters, fires, and deforestation. Satellites also reveal how widespread changes in vegetation impact waterways,&nbsp; the climate, air quality. Satellites communicate by using radio waves to send signals to the antennas on the Earth. "Earth From Space" is a groundbreaking two-hour special that reveals a spectacular new space-based vision of our planet. 



Video Credit: NASA Goddard&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Satellites reveal how Earth's systems are interconnected

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